Milrinone

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Intravenous milrinone in cardiac surgery.

Phosphodiesterase inhibitors including milrinone produce positive inotropic effects by slowing the hydrolysis of cyclic adenosine monophosphate in the myocardium. With a loading dose of 50 microg/kg followed by an infusion of 0.5 microg x kg(-1) x min(-1), milrinone increases stroke volume index and left ventricular velocity of circumferential fiber shortening after weaning from cardiopulmonary...

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Levosimendan versus milrinone for pediatric cardiac surgery

BACKGROUND: Our aim is to check effectiveness of intravenous Levosimendan in comparison with intravenous Milrinone in congenital heart surgery with cardiopulmonary bypass. MATERIALS AND METHODS: 50 Paediatric patients between 2 months to 12 years of age divided into two groups. Group L (n=25) received inj. levosimendan 12μg/kg over 10 minutes1 after cross clamp removal and 0.1μg/kg/min started ...

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Milrinone in Enterovirus 71 Brain Stem Encephalitis

Enterovirus 71 (EV71) was implicated in a widespread outbreak of hand-foot-and-mouth disease (HFMD) across the Asia Pacific area since 1997 and has also been reported sporadically in patients with brain stem encephalitis. Neurogenic shock with pulmonary edema (PE) is a fatal complication of EV71 infection. Among inotropic agents, milrinone is selected as a therapeutic agent for EV71- induced PE...

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Use of milrinone in critically ill children.

BACKGROUND Optimal dose adjustment of milrinone in critically ill children is challenging because of conflicting information about the association between dose and outcomes in this age group. OBJECTIVES To describe the use of milrinone in critically ill children and to explore associations between milrinone dosing and clinical outcomes, specifically effectiveness and adverse events. METHODS...

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Treatment Of Milrinone Induced Hypotension With Vasopressin

The standard of treatment of decompensated class IV congestive heart failure (CHF) usually involves positive ionotropic agents such as continuous infusion of dobutamine. When this is inadequate, or the patient is unable to tolerate the dobutamine, secondary to refractory tachycardia/malignant arrhythmia, phosphodiesterase inhibitors, such as Milrinone/Amrinone are commonly employed. The mechani...

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ژورنال

عنوان ژورنال: Journal of Veterinary Internal Medicine

سال: 1990

ISSN: 0891-6640,1939-1676

DOI: 10.1111/j.1939-1676.1990.tb03107.x